SPIROKETAL LIBRARY

A library of spiroketals diversified through three independently addressable functional groups
Reference : “Combinatorial Synthesis of Natural Product-like Molecules Using a First Generation Spiroketal Scaffold,” Kulkarni, B.A.; Roth, G. P.; Lobkovsky, E.; Porco, J. A., Jr. J. Comb. Chem., 2002, 4, 56-72.
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EPOXYQUINOL LIBRARY

A chemical library of angular epoxyquinol scaffolds with distinct skeletal frameworks.
Reference : “Stereocontrolled Synthesis of a Complex Library via Elaboration of Angular Epoxyquinol Scaffolds,” Lei, X.; Zaarur, N.; Sherman, M. Y.; Porco, J. A., Jr. J. Org. Chem., 2005, 70, 6474-6483.
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OXIME LIBRARY

A chemical library of complex hybrid oximes.
Reference : “Convergent Synthesis of a Complex Oxime Library Using Chemical Domain Shuffling,” Su, S.; Acquilano, D. E.; Arumugasamy, J.; Beeler, A. B.; Eastwood, E. L.; Giguere, J. R.; Lan, P.; Lei, X.; Min, G. K.; Yeager, A. R.; Zhou, Y.; Panek, J. S.; Snyder, J. K.; Schaus, S. E.; Porco, J. A., Jr. J. Org. Lett., 2005, 7, 2751-2754.
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MACRODIOLIDE LIBRARY

A library of highly diverse and stereochemically well-defined macrodiolides.
Reference : “Synthesis of a Library of Complex Macrodiolides Employing Cyclodimerization of Hydroxy Esters," Beeler, A. B.; Acquilano, D. E.; Su, Q.; Yan, F.; Roth, B. L.; Panek, J. S.; Porco, J. A., Jr. J. Comb. Chem., 2005, 7, 673-681.
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DIKETOPIPERAZINE LIBRARY

A small library of complex diketopiperazines.
Reference : “Convergent Synthesis of Complex Diketopiperazines Derived from Pipecolic Acid Scaffolds and Parallel Screening against GPCR Targets," Dandapani, S.; Lan, P.; Beeler, A. B.; Beischel, S.; Abbas, A.; Roth, B. L., Porco, J. A.,Jr.; Panek, J. S. J. Org. Chem., 2006, 71, 8934-8945.
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CYCLIC ETHER LIBRARY

A small library of novel cyclic ethers.
Reference : “Exploring Skeletal Diversity via Ring Contraction of Glycal-Derived Scaffolds," Yeager, A. R.; Min, G. K.; Porco, J. A., Jr.; Schaus, S. E. Org. Lett., 2006, 8(22), 5065-5068.
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